The area is renowned for its cultural and environmental amenities, beaches, resorts, connections to the Ringling family, Amish community, and the Sarasota School of Architecture. The city is located at the southern end of the Tampa Bay Area, north of Fort Myers.

The Naples area is home to several major land reserves, including the Corkscrew Swamp Sanctuary, Everglades National Park, Big Cypress National Preserve, Florida Panther National Wildlife Refuge, Ten Thousand Islands National Wildlife Refuge, and Picayune Strand State Forest. The Corkscrew Swamp Sanctuary is known not only for its 11,000 acres of landscape and wildlife, but for a two and a half-mile long boardwalk winding through the sanctuary The Naples area is also home to the Naples Zoo at Caribbean Gardens, which dates back to 1919.